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Indicator 4.4.12
by Contact on 8 October 2026
Requirement
The UoC shall not use8484Batches treated with antimicrobials listed as Critically Important Antimicrobials for Human Medicine are not eligible for ASC certification. antimicrobials listed as Critically Important Antimicrobials (CIA) for Human Medicine by the World Health Organisation (WHO).8585https://www.who.int/publications/i/item/9789241515528 An exception applies where the following can be demonstrated: a) all other available antimicrobials are not effective, or there is no availability of antimicrobials other than the CIA; and b) previous monitoring has not determined build-up of antimicrobial resistance. A registered veterinarian shall provide a written justification for the use of any CIA under the exceptional circumstances listed above.
How Do I Interpret This Requirement?
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The use of CIA is not allowed unless they are the only possible treatment option and there is no indication of resistance.
Evidence of Implementation
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If CIA are used, the decision should be documented.
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Specific registered veterinarian justification should be in place, including evidence that there is no resistance towards the selected CIA.
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Auditors Should Confirm
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Veterinary considerations for the use of CIA and resistance testing.
Useful Resources
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Luthman, O., Robb, D.H.F., Henriksson, P.J.G., J∅rgensen, P.S. & Troell, M. (2024) Global overview of national regulations for antibiotic use in aquaculture production. Aquaculture International.
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Responsible Use of Medicines In Agriculture Alliance (2004) Responsible use of antimicrobials in fish production. RUMA Alliance Guidelines 21pp.
